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The Food and Drug Administration on Friday approved a drug intended to treat postpartum depression. This is the first oral treatment to treat depressive disorders that affect childbirth. Estimate 1 in 7 women after giving birth.
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of FDA Sage Therapeutics and Biogen have approved a drug called zranolone manufactured in tablet form under the name ‘Drugfly’. Said Can the drug “provide rapid improvement” in women experiencing symptoms of postpartum depression, including cognitive impairment, sadness and helplessness, low energy and suicidal thoughts?
Zranolon the work As a neuroactive steroid that binds to GABA receptors in the brain, it resets imbalanced neurotransmitters in people with certain disorders. include Depression, schizophrenia, and other mood disorders.
Drift flies were tested in two randomized, double-blind trials (where neither the participants nor the experimenters knew who was receiving the placebo), and patients given 50 mg of dander were more likely to die after 15 days. Symptoms were shown to be “significantly improved” compared to patients who received 50 milligrams of dregs. placebo group.
Christina Deglijannidis, director of women’s behavioral health at New York-based Zucker Hillside Hospital, said: Said luck The drug is notable for its ability to provide “rapid relief of depressive symptoms” in as little as three days.
The FDA also requested additional studies of the drug in adults experiencing other major depressive disorders. 8.3% Both companies said they are considering next steps.
The companies said the pill will be on the market within 90 days after the FDA schedules it as a controlled substance.
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Samantha Meltzer Brody, director of the Center for Women’s Mood Disorders at the University of North Carolina at Chapel Hill. Said of washington post The drug “will revolutionize the treatment of maternal depression.”
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Half a million. According to Postpartum Support International, this is the estimated number of women in the United States who experience symptoms of postpartum depression each year.
main background
Postpartum depression is also called “baby blues” experienced Some women experience symptoms after giving birth, but most women tend to have less symptoms in the first two weeks after giving birth.symptoms start often It occurs within the first few days after birth, sometimes during pregnancy, and can last for years.as much as you want half The proportion of mothers who experience postpartum depression do not reveal their symptoms. An estimated 20% of maternal deaths after childbirth are attributed to suicide. according to Contact the Mother’s Mental Health Policy Center. Before the FDA approved zranolone, the only federally approved treatment for postpartum depression was: Brexanolonea drug marketed as Zresso, available only by infusion.
References
FDA approves first oral drug for postpartum depression (Reuters)
FDA Approves Zranolone, First Drug for Postpartum Depression (CBS)
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