We’re reading about Pfizer GLP-1 halt, FDA use of contractors

Good morning, everyone, and welcome to another work week. I hope that your weekend rest will relax and refresh you. Because once again, those predictable meetings and deadlines have returned. After all, the world continues to spin. And yes, we rely on a cup of stimulation to help us. Our choice today is pumpkin spices. Please feel free to join us. No prescription is required. Meanwhile, here’s some information to get you going. I hope your day is simply broken and stays in touch. We enjoy your notes and documents. …

To close out the two-year inventory play drama, Pfizer says it will stop the development of Danuglipron, an experimental oral GLP-1 medicine to treat obesity, focusing efforts on another drug mechanismI write the statistics. The company revealed that asymptomatic volunteers in its study experienced “potential drug-induced liver damage.” After reviewing all clinical data for the drug and consulting with regulators, Pfizer decided to suspend the study. The news could be bothering investors as the vast potential for selling obesity drugs and the need for Pfizer must demonstrate advances in its drug research. Pfizer stocks have fallen almost 18% since the start of the year, trading at about a third of its peak during the pandemic era. Some analysts expressed optimism about the Danuglipron program, based in part on comments from Pfizer executives.

The U.S. Food and Drug Administration has finalised plans to replace some of the employees who laid off to contractors after the agency’s workforce suspended drug and food safety inspections., CBS News Report. Contractors effectively replace most of the work done by more than 50 laid-off federal employees who handled travel logistics and conducted oversights on spending to agents inspectors. The plan was approved by FDA Commissioner Marty McCurry. The move appears to be inconsistent with what layoff workers in support of the FDA testing and investigation office were communicated in the layoff notification. Their work was “unnecessarily or substantially identical to the obligations carried out elsewhere in the institution.”