Top line:
Compared to a healthy omnivore diet, a healthy vegan diet led to significant improvements in healthy eating. low density lipoprotein cholesterol (LDL-C) as well as fasting insulin Weight loss in a randomized controlled trial of identical twins.
methodology:
- Researchers randomized 22 pairs of healthy adult identical twins (34 females, mean age 39 years, mean body mass index 25.9) to a healthy vegan or omnivore diet (one twin per pair). Assigned.
- For the first 4 weeks, diet-specific meals were provided through a meal delivery service. During the last four weeks, participants prepared meals/snacks appropriate to their diet.
- The primary outcome was change in LDL-C. Secondary outcomes included changes in body weight and fasting insulin.
remove:
- After eight weeks, the twins eating the vegan diet showed a significant reduction in LDL-C by an average of 13.9 mg/dL compared to the twins eating the omnivore diet.
- The vegan diet also produced a significant reduction in fasting insulin levels by an average of 2.9 μIU/mL and body weight by 1.9 kg after 8 weeks compared to the omnivore diet, although weight loss was observed in both dietary groups. it was done.
- In the vegan diet group, the absolute median decrease during fasting was greater but not significant. HDL-C, Neutral fatvitamin B12, glucose, and trimethylamine N-oxide levels over 8 weeks.
in fact:
“Our results confirm previous findings that eating a vegan diet improves cardiovascular health. Clinicians should not only reconcile environmental benefits but also monitor cardiometabolic risk factors. “We may consider recommending a plant-based diet to reduce this,” the researchers concluded.
sauce:
The study was written by lead author Matthew J. Landry, PhD, RDN, of the Stanford Prevention Research Center, Stanford University School of Medicine, California. Published online November 30th JAMA network open.
Limitations:
The adult twin population is generally healthy, and this result may not be generalizable to other populations. The small sample size, short intervention period, and lack of follow-up limited insight into dietary stability and sustainability.
Disclosure:
Funding was provided by the Voigt Foundation, with grants from Stanford University and the National Heart, Lung, and Blood Institute. Landry has no relevant disclosures. One author reported receiving funding from Beyond Meat separately from this study.
