The 62-year-old Massachusetts man who became the first person in the world to successfully transplant a gene-edited pig kidney was discharged from a Boston hospital on Wednesday. Weymouth resident Richard Suleiman, who has end-stage renal disease, underwent a successful transplant at Massachusetts General Hospital last month. It was announced to the world a few days later. In his statement regarding his release, Mr. Suleiman celebrated the opportunity to enjoy his life without the burden of his illness. “Today, this moment of being able to leave the hospital in the best state of health I’ve had in a long time, is the moment I’ve wanted to come for years.” It was one of my happiest moments. I would like to thank everyone at Massachusetts General Hospital who took care of me before and after my historic transplant, especially Dr. Williams, Dr. Riera, Dr. Ta. “Mr. Suleiman’s surgery on March 16 took about four hours. The hospital said it was a major milestone in its quest to provide more readily available organs to patients.” The care I received was exceptional and I trust the doctors at Massachusetts General Brigham Health System with my life. I am free from the burden of dialysis and can once again spend time with my family, friends, and loved ones. I’m excited to be here,” Suleiman said. It has affected my quality of life for many years. Lastly, I would like to thank everyone who has seen my story and sent their well wishes, especially the patients waiting for a kidney transplant. Today is a new beginning not only for me but also for them. My recovery is progressing well and I ask for your privacy at this time. ” Suleiman, who had long suffered from type 2 diabetes and high blood pressure, had undergone dialysis seven years ago before receiving a kidney transplant from a deceased human donor in December 2018. Video: Exclusive interview with the doctor Suleiman resumed dialysis in May 2023, nearly five years after the transplanted human kidney showed signs of failure. Since restarting her dialysis, dialysis vascular access complications have recurred, requiring visits every two weeks for clot removal and surgical correction, greatly impacting her quality of life and making her a common problem. I was also holding. Suleiman said a team of nephrologists and the transplant center suggested a pig kidney transplant and carefully explained the pros and cons of the procedure. “He asked me, do you think it’s going to hurt me? Do you think it’s going to be effective? Do you trust Dr. (Leonardo) Riera and the team that’s bringing this into the clinic? If you told me I had it, I would give it another try because after this transplant there is a good chance that I will grow and be off dialysis,” said Winfred, vice chairman of MGH’s Renal Division. Dr. Williams said. “He was completely exhausted by the failures he had experienced with dialysis. Another thing he said was that he hoped dialysis would do me good. I knew that his quality of life would be restored if he showed his true self.”But he also said that I could also do good for others who would come after me.” “The latest history-making kidney transplant was completed nearly 70 years after Army General Brigham performed the world’s first successful human kidney organ transplant in 1954.” This is the culmination of efforts by human scientists and physicians,” said Dr. Tatsuo Kawai, director of the Legorreta Clinical Transplant Tolerance Center. “Our hope is that this transplant approach will provide a lifeline to the millions of patients around the world suffering from kidney failure.” It was gene-edited using technology to remove harmful substances. Certain human genes were added to the pig’s genes to make them more compatible with humans. Video below: Doctors announce historic success. Transplant nephrologist Leonardo Riera became emotional in a statement describing the patient and the procedure. “We thoroughly discussed all the known and unknown risks of the surgery with the patient multiple times, and he made the courageous decision to proceed with the xenotransplant,” he said. “We would like to express our deep gratitude to our MGH team.” The hospital said the scientists also inactivated the endogenous porcine retrovirus in the pig donor to eliminate the risk of infection to humans. Stated. The successful procedure in a living recipient is a historic milestone in the emerging field of xenotransplantation. – Transplantation of organs or tissues from one species to another – as a potential solution to the global organ shortage. The procedure was performed under a single FDA expanded access protocol (known as compassionate use) and was authorized for a single patient or group of patients. This video is about making experimental treatments and clinical trials available for serious and life-threatening diseases and conditions when no comparable treatments or treatments exist. Video below: Hospital leaders discuss historic transplant. Video below: Bioethics consultant shares concerns about ensuring transplant equity.
The 62-year-old Massachusetts man who became the first person in the world to successfully transplant a gene-edited pig kidney was discharged from a Boston hospital on Wednesday.
Weymouth resident Richard Suleiman, who has end-stage renal disease, underwent a successful transplant at Massachusetts General Hospital last month. It was announced to the world a few days later.
In a statement regarding his release, Suleiman celebrated the opportunity to enjoy life without the burden of illness.
“Today, this moment of being able to leave the hospital in the best state of health I’ve had in a long time, is the moment I’ve wanted to come for years.” It was one of my happiest moments. I would like to thank everyone at Massachusetts General Hospital who took care of me before and after my historic transplant, especially Dr. Williams, Dr. Riera, Dr. Ta. Mr. Kawai and the countless nurses who took care of me every day during my stay. ”
Suleiman’s surgery on March 16 took about four hours. The hospital says the operation marks a major milestone in its quest to provide more readily available organs to patients.
“The care I received was exceptional and I trust the doctors at the Massachusetts General Brigham Health System with my life,” Suleiman said. “I am excited to be free from the burden of dialysis, which has affected my quality of life for many years, and to be able to spend time with my family, friends, and loved ones again. “I would like to thank everyone who has sent me such kind messages. Especially with the wishes of the patients waiting for a kidney transplant. Today is a new beginning not only for me, but also for them. My recovery is Things are going well and we ask for privacy at this time.”
Suleiman, who had long suffered from type 2 diabetes and high blood pressure, received a kidney transplant from a deceased human donor in December 2018 after undergoing dialysis seven years ago.
Video: Exclusive interview with a doctor
The transplanted human kidney showed signs of malfunctioning after about five years, and Suleiman restarted dialysis in May 2023. Since restarting her dialysis, dialysis vascular access complications have recurred, requiring visits every two weeks for clot removal and surgical correction, which has significantly impacted her life. His quality of life and issues common to dialysis patients.
Suleiman said a team of nephrologists and the transplant center suggested a pig kidney transplant and carefully explained the pros and cons of the procedure.
“He asked me, do you think it’s going to hurt me? Do you think it’s going to be effective? Do you trust Dr. (Leonardo) Riera and the team that’s bringing this into the clinic? If you told me I had it, I would give it another try because after this transplant there is a good chance that I will grow and be off dialysis,” said Winfred, vice chairman of MGH’s Renal Division. Dr. Williams said. “He was completely exhausted by the failures he had experienced with dialysis. Another thing he said was that he hoped dialysis would do me good. But he also said, “I can do good to others who come after me.” I did.
The latest history-making kidney transplant was completed nearly 70 years after Army General Brigham performed the world’s first successful human kidney organ transplant in 1954.
“This successful transplant is the culmination of decades of hard work by thousands of scientists and physicians,” said Dr. Tatsuo Kawai, director of the Legorreta Clinical Transplant Tolerance Center. “Our hope is that this transplant approach will provide a lifeline to the millions of patients around the world suffering from kidney failure.”
The pig kidneys were donated by pig donors to EGenesis, a company in Cambridge, Mass., that uses technology to remove harmful pig genes and add specific human genes to improve compatibility with humans. It was gene-edited using
Video below: Doctors announce historic success
Dr. Leonardo Riera, a transplant nephrologist, became emotional in a statement describing the patient and the procedure.
“We thoroughly discussed all known and unknown risks of the surgery with the patient multiple times, and the patient bravely made the decision to proceed with the xenotransplant,” he said. “A big thank you to our MGH team.”
The hospital said scientists also inactivated the donor pig’s endogenous retrovirus to eliminate the risk of infection to humans.
Successful surgeries in living recipients have made history in the emerging field of xenotransplantation (the transplantation of organs and tissues from one species to another) as a potential solution to the global organ shortage. It will be a milestone.
This procedure is permitted for a single patient or group of patients with a serious, life-threatening disease or condition to gain access to experimental treatments or clinical trials in the absence of comparable treatment options or treatments. , was made under the single FDA Expanded Access Protocol known as Compassionate Use. exist.
Video below: Hospital leaders talk about historic transplant
Video below: Bioethics consultant shares concerns about ensuring transplant equity
