Weight-loss drugs have become a hot topic as public health officials and pharmaceutical companies seek solutions to the growing global obesity epidemic.
Florian Gärtner | Phototech | Getty Images
Ann oral medicine Pfizer-made Ozempic caused weight loss similar to rival Novo Nordisk’s blockbuster injectable Ozempic, and faster, according to a peer-reviewed study of results from a phase II clinical trial released Monday. It is said to be effective.
The results were presented at a medical conference late last year.but JAMA network It is the only time to publish a peer-reviewed study.
The Pfizer trial followed 411 adults with type 2 diabetes who took the company’s drug. Danuglipronetwice daily, or placebo.
The study found that patients who took the 120-milligram version of danugliprone lost an average of about 10 pounds (4.60 kilograms) in 16 weeks.
The study did not directly compare Pfizer’s drugs with Ozempic.
However, a Phase 3 clinical trial of Ozempic found that adults who took the 1-milligram injection lost an average of about 9.9 pounds over 30 weeks. Patients receive the injection once a week.
This result suggests that danugliprone may be as effective on body weight as Ozempic.
Pfizer’s drug may also offer advantages as an oral treatment option rather than frequent injections.
Both danugliprone and ozempic are part of a class of drugs called glucagon-like peptide-1 antagonists.
They mimic a hormone produced in your gut called GLP-1 that signals your brain when you’re full.
These drugs also help manage type 2 diabetes by increasing insulin release from the pancreas and lowering blood sugar levels.
New York-based Pfizer is the latest pharmaceutical company to enter the blockbuster weight loss drug market.
Novo Nordisk’s Ozempic and Wegobee have gained national attention in recent years as a weight loss ‘miracle’.
Hollywood Celebrity, Social Media Influencer, Billionaire Tech Mogul Elon Musk He reportedly used popular injections to shed unwanted weight.
However, experts To tell The drug may further perpetuate a dangerous dietary culture that idealizes weight loss and leanness.
Some patients who stop taking the drug complain of weight rebound that is difficult to control.
More than 2 in 5 adults are obese, according to the WHO. National Institutes of Health. About 1 in 11 adults is severely obese.
