Home Medicine Paracetamol, cetirizine among 156 combination drugs banned by Indian government; several multivitamins under review

Paracetamol, cetirizine among 156 combination drugs banned by Indian government; several multivitamins under review

by Universalwellnesssystems
The Indian government has banned the use of several drugs, including the mixing and concomitant use of various drugs, as a measure to make public health safer and more convenient.
As a result, 34 Multivitamin Following the recent ban of 156 medicines, Government of India According to sources, the company is now considering banning 34 more multivitamins. “34 multivitamins are under evaluation based on the review,” a source told news agency ANI.
The official gazette notice in which the government announced the ban said, “The matter was examined by an Expert Committee appointed by the Central Government, which after thorough consideration of the entire matter, found these FDCs to be unreasonable. The Drugs Technical Advisory Committee has also examined these FDCs and recommended that the ingredients contained in them have no therapeutic justification and are likely to pose a hazard to humans.” The notice further states, “In wider public interest, it is necessary to prohibit the manufacture, sale or distribution of these FDCs under Section 26A of the Drugs and Cosmetics Act, 1940. Based on the recommendations of the Drugs Technical Advisory Committee, the Central Government is satisfied that it is necessary and expedient in public interest to prohibit the sale, manufacture for human use, sale or distribution of the above-mentioned drugs in the country.”

Common Prohibited Drug Combinations

It is very important that the public be aware of prohibited drug combinations.
Among the banned combinations was the FDC of amylase + protease + glucoamylase + pectinase + alpha-galactosidase + lactase + beta-gluconase + cellulase + lipase + bromelain + xylanase + hemicellulase + malt diastase + invertase + papain, which was immediately banned. Paracetamol Injections can be dangerous to the human body and are also prohibited. Ergotamine tartrate + caffeine + paracetamol + prochlorperazine maleate are also prohibited.
Fourteen drug combinations were banned in June last year. In 2016, 344 drug combinations were banned from public use.

Why are drug combinations prohibited?

Concomitant use of drugs is often prohibited due to concerns about safety and efficacy. Taking certain drugs together can lead to unpredictable and potentially dangerous interactions. These interactions can increase or decrease the effectiveness of one or both drugs and can cause harmful side effects. For example, the combination of some drugs can cause serious side effects such as organ damage, cardiovascular problems, and allergic reactions. Regulatory agencies impose bans to protect patients from these risks and ensure that treatment is safe and effective. For example, the combination of ergotamine tartrate + caffeine + paracetamol + prochlorperazine maleate can cause stomach irritation, dizziness, and insomnia.
Drug combinations are also prohibited when there is insufficient evidence of benefit or efficacy. If the drug combination does not provide a clear therapeutic advantage over the use of the individual drugs or if the combination does not effectively address symptoms, the combination may be deemed unnecessary. This precaution prevents patients from being exposed to potentially harmful or ineffective treatments.

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