Colon cancer could be stopped by turning on a protein ‘like a light switch’: study

health

by alex mitchell

This could be a breakthrough in colon cancer prevention.

Researchers at the Australian National University have learned how to use drugs to activate cancer-fighting proteins, removing damaged DNA from the body “like a light switch”.

“In its activated state, this protein acts like a surveillance system, detecting signs of damaged DNA within cells,” said researcher Abhimanu Pandey, Ph.D. Talked about protein Ku70.

He added that “DNA damage” is typically an early warning sign that a cell may become cancerous. Ku70 has the potential to reverse or at least stop the damage.

“Our study shows that Ku70 can 'cool' cancer cells and remove damaged DNA. This protein prevents cancer cells from becoming more aggressive and spreading throughout the body, essentially keeping them inactive and dormant. ”

126,240 cases of colorectal cancer in the United States reported Centers for Disease Control and Prevention in 2020.

That year, 51,869 people died.

According to the study, 100 people die from bowel cancer every week in Australia, where the study was conducted.

However, data currently published in Science Advances suggests that if detected early, 90% of cases can be successfully treated.

“We know that early detection and treatment are essential to overcome not only colorectal cancer, but also the potential for other cancers,” said researcher Shi Ming Man Man. Stated.

Professor Mann added that screening for cancers such as colon may soon include testing for Ku70 levels.

“Our study shows that Ku70 is a good immune biomarker, meaning it can help predict who will do better and who will do worse after being diagnosed with colorectal cancer. .”